What is ertapenem sodium used for?

Ertapenem injection is used to treat certain serious infections, including pneumonia and urinary tract, skin, diabetic foot, gynecological, pelvic, and abdominal (stomach area) infections, that are caused by bacteria. It is also used for the prevention of infections following colorectal surgery.

What is the drug Invanz used to treat?

Invanz is an antibiotic that is used to treat severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract. Invanz is also used to prevent infection in people having certain types of surgery.

What is the pH of ertapenem?

The sodium content is approximately 137 mg (approximately 6.0 mEq). Each vial of INVANZ contains the following inactive ingredients: 175 mg sodium bicarbonate and sodium hydroxide to adjust pH to 7.5.

Does ertapenem sodium need to be diluted?

Preparation for intravenous administration: INVANZ MUST BE RECONSTITUTED AND THEN DILUTED PRIOR TO ADMINISTRATION.

Is Invanz a strong antibiotic?

Invanz (ertapenem for injection) is a type of antibiotic used to treat severe infections of the skin, lungs, stomach, pelvis, and urinary tract. Invanz is also used to prevent infection in people having certain types of surgery….

Adverse Events INVANZ 1 g (N = 476) Cefotetan 2 g (N = 476)
Atelectass 3.4 1.9

What bacteria does ertapenem cover?

Ertapenem, a carbapenem antibacterial, has in vitro activity against many Gram- negative (including Enterobacteriaceae) and Gram-positive aerobic and anaerobic bacteria that are commonly associated with various infections.

What are the side effects of Invanz?

Swelling, redness, pain, or soreness at the injection site may occur. Upset stomach, headache, nausea, vomiting, or diarrhea may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What type of antibiotic is Invanz?

Ertapenem is used to prevent and treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic. It works by stopping the growth of bacteria.

Does Invanz have penicillin?

Invanz is also used to prevent infection in people having certain types of surgery. Both Zosyn and Invanz contain a beta-lactamase inhibitor. Zosyn also contains a penicillin antibiotic.

How long is ertapenem IV good for?

Intravenous administration: INVANZ should be infused over a period of 30 minutes. The usual duration of therapy with INVANZ is 3 to 14 days but may vary depending on the type and severity of infection and causative pathogen(s).

How often is Invanz given?

The recommended dose of ertapenem in adult patients with CLCR ≤30 mL/min/1.73 m2 is 0.5 grams every 24 hours. Following a single 1 g IV dose given immediately prior to a 4 hour hemodialysis session in 5 adult patients with end-stage renal insufficiency, approximately 30% of the dose was recovered in the dialysate.

What are the possible adverse reactions to Invanz?

The most common adverse reactions (≥5%) in pediatric patients treated with INVANZ, including those who were switched to therapy with an oral antimicrobial, were diarrhea, vomiting and infusion site pain. ( 6.1)

How much Ertapenem is in Invanz?

Each vial contains 1.046 grams ertapenem sodium, equivalent to 1 gram ertapenem. The sodium content is approximately 137 mg (approximately 6.0 mEq). Each vial of INVANZ contains the following inactive ingredients: 175 mg sodium bicarbonate and sodium hydroxide to adjust pH to 7.5.

What is the difference between add-Vantage® and Invanz?

INVANZ is a sterile lyophilized powder in a vial containing 1.046 g ertapenem sodium equivalent to 1 g ertapenem for intravenous infusion or for intramuscular injection. INVANZ is a lyophilized powder in an ADD-Vantage® vial containing 1.046 g ertapenem sodium equivalent to 1 g ertapenem for intravenous infusion.

How do you reconstitute Invanz?

Reconstitute the contents of a 1 g vial of INVANZ with 10 mL of one of the following: Water for Injection, 0.9% Sodium Chloride Injection or Bacteriostatic Water for Injection. Shake well to dissolve and immediately transfer contents of the reconstituted vial to 50 mL of 0.9% Sodium Chloride Injection.