What is HPV aptima?

The Aptima HPV assay detects E6/E7 mRNA, which is indicative of those HPV infections more likely to cause cervical disease. The Aptima HPV 16 18/45 genotype assay identifies HPV types 16, 18 and 45, which are associated with up to 80% of all invasive cervical cancers worldwide.

How accurate is HPV aptima test?

The Aptima HPV assay showed a clinical sensitivity for CIN2+ of 94.2% (95% confidence interval [CI], 85.5 to 97.8%) and a clinical specificity for CIN2+ of 94.5% (95% CI, 92.8 to 95.9%); by comparison, these figures were 97.1% (95% CI, 89.1 to 99.3%) (67/69 samples) and 93.6% (95% CI, 91.7 to 95.0%) (785/839 samples).

What does it mean when your Pap smear comes back positive for HPV?

If the results of your Pap test come back positive, that means your doctor found abnormal or unusual cells on your cervix. It doesn’t mean you have cervical cancer. Most often, the abnormal test result means there have been cell changes caused by the human papilloma virus (HPV).

Is aptima approved for primary HPV screening?

The widely used Hologic Aptima HPV assay is not approved for primary screening. “Both the Cobas and Aptima have been around for a while and are good tests,” Dr. Davey says.

Should I be worried about HPV positive?

A positive test result means that you have a type of high-risk HPV that’s linked to cervical cancer. It doesn’t mean that you have cervical cancer now, but it’s a warning sign that cervical cancer could develop in the future.