Is ondansetron HCL safe during pregnancy?

Zofran is approved by the Food and Drug Administration (FDA) for use to fight off nausea related to chemotherapy. It is not currently approved by the FDA for morning sickness. Even so, most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness.

What are the risks of taking ondansetron while pregnant?

Ondansetron: small increased risk of oral clefts following use in the first 12 weeks of pregnancy. Recent epidemiological studies suggest exposure to ondansetron during the first trimester of pregnancy is associated with a small increased risk of the baby having a cleft lip and/or cleft palate.

Does Zofran cause miscarriage?

There are no studies that have looked to see if ondansetron could make it harder for a person to get pregnant. Studies in animals did not find that ondansetron would affect the ability to get pregnant. Does taking ondansetron increase the chance for miscarriage? Miscarriage can occur in any pregnancy.

How bad is Zofran during pregnancy?

If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small.

Does ondansetron cause birth defects?

Taking Ondansetron During Pregnancy Does Not Appear to Increase Risk For Birth Defects.

What nausea medicine can you take while pregnant?

In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.

How much ondansetron is safe during pregnancy?

Typical dosage for pregnancy nausea The dose of Zofran for hyperemesis gravidarum requiring hospitalization is a maximum of 10 milligrams via intravenous therapy (IV) every 8 hours. More typical pregnancy nausea is managed by a much lower oral dose — 4 to 8 mg every 8 hours.

Is Zofran safe during pregnancy second trimester?

A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus.

How often can you take ondansetron while pregnant?

Does ondansetron help morning sickness?

Ondansetron (Zofran®) is a medicine used to treat nausea and vomiting that may be caused by surgery, chemotherapy, or radiation therapy. Healthcare professionals also prescribe ondansetron during pregnancy to reduce symptoms of nausea and vomiting, also known as “morning sickness.”

Does ondansetron help with morning sickness?

Why is ondansetron given for hyperemesis gravidarum?

Ondansetron is a very effective medicine that works by blocking the action of chemicals in the body that trigger nausea and vomiting. Ondansetron can greatly improve quality of life in women with hyperemesis gravidarum, as well as helping to prevent the serious complications that can be caused by this condition.

Are there any pregnancy warnings for ondansetron?

Ondansetron Pregnancy Warnings. AU TGA pregnancy category B1: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed.

What are ondansetron tablets used for?

Ondansetron tablets are indicated for the prevention of nausea and vomiting associated with: Ondansetron tablets are also indicated for the prevention of postoperative nausea and/or vomiting. Ondansetron tablets are contraindicated in patients:

What are the side effects of Adderall (ondansetron)?

high levels of serotonin in the body–agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting. Common ondansetron side effects may include: tired feeling. This is not a complete list of side effects and others may occur.

What should I do if I overdose on ondansetron?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. What should I avoid while taking ondansetron (Zofran, Zofran ODT, Zuplenz)?