What class of drug is amantadine?

Amantadine is in a class of medications called adamantanes. It is thought to work to control movement problems by increasing the amount of dopamine in certain parts of the body. It works against influenza A virus by stopping the spread of the virus in the body.

What is amantadine FDA approved for?

On August 24, 2017, the US Food and Drug Administration (FDA) approved amantadine (Gocovri; Adamas Pharmaceuticals), an oral, extended-release drug for the treatment of dyskinesia in patients with Parkinson’s disease who receive levodopa-based therapy, with or without concomitant dopaminergic medications.

Why is amantadine contraindicated in pregnancy?

Comment: -It is generally best to avoid this drug because of its potential negative effects on lactation.

Is amantadine HCL the same as amantadine?

For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. SYMMETREL (Amantadine Hydrochloride, USP) is designated generically as amantadine hydrochloride and chemically as 1-adamantanamine hydrochloride.

Is amantadine an immunosuppressant?

Unlike other immunosuppressive agents, this chemical appears to affect only the proliferative response of cells in systems relating to immunological recognition. Phytohemagglutinin (PHA) stimulation of the same cell population is enhanced by amantadine.

Is amantadine an anticholinergic?

Amantadine is a weak, non-competitive antagonist of the NMDA receptor, which increases dopamine release and prevents dopamine reuptake. Although amantadine does not have anticholinergic activity, there may be anticholinergic side effects such as dry mouth, urinary retention, and constipation clinically.

When is amantadine indicated?

SYMMETREL (amantadine hydrochloride) is indicated for the prophylaxis and treatment of signs and symptoms of infection caused by various strains of influenza A virus. SYMMETREL (amantadine hydrochloride) is also indicated in the treatment of parkinsonism and drug-induced extrapyramidal reactions.

Is amantadine HCl the same as amantadine?

What classification of antiviral drug is acyclovir?

Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body.

What is another name for amantadine?

Amantadine oral capsule is available as a brand-name drug and a generic drug. Brand name: Gocovri.

Is amantadine an Nsaid?

Amantadine (brand names: Symmetrel®, Gocovri®, Osmolex ER®, Endantadine®) is an antiviral medication that also has some pain control effects. Its use in small animals is primarily for the treatment of pain, and it is often paired with other pain medications such as NSAIDs, opioids, or gabapentin.

What is amantadine hydrochloride used to treat?

Amantadine Hydrochloride is the hydrochloride salt of amantadine, a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain…

What is the molecular formula of amantadine?

Amantadine PubChem CID 2130 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C10H17N Synonyms amantadine 1-Adamantanamine 768-94-5

Is Amantadine an antiparkinson drug?

Pharmacology Pharmacology information related to this record. Amantadine is an antiviral drug which also acts as an antiparkinson agent, for which it is usually combined with L-DOPA when L-DOPA responses decline (probably due to tolerance). It is a derivate of adamantane, like a similar drug rimantadine.

Does amantadine cause liver damage?

Amantadine is a primary amine that has both antiviral and dopaminergic activity and is used in the therapy of influenza A and management of Parkinson disease. Amantadine has not been associated with clinically apparent liver injury. Amantadine is a member of the class of adamantanes that is used as an antiviral and antiparkinson drug.