Why there is no vaccine for schistosomiasis?
No effective vaccine for the disease exists yet. Schistosomiasis affects over 200 million people worldwide, mainly in rural agricultural and peri-urban areas of developing countries, and approximately 10% suffer severe health complications from the infection.
Who developed a vaccine against schistosomiasis?
Since its development by Bayer in the 1970s, mass drug administration (MDA) of praziquantel (PZQ)  has been the main strategy for the control of schistosomiasis .
How a vaccine could protect people from schistosomiasis?
A vaccine would contribute to the reduction of schistosomiasis morbidity through induced immune responses leading to decrease in parasite load and reduced egg production. This vaccine could be administered to children between the ages of 3 and 12 years to prevent severe infection in a particularly high risk population.
Can schistosomiasis affect the brain?
Central nervous system involvement is a rare ectopic manifestation of schistosomiasis. It has been explained that the schistosome eggs are small and could reach the brain easily. The brain disease is caused by the host reaction to schistosome eggs.
How can schistosomiasis be prevented?
Preventing schistosomiasis avoid paddling, swimming and washing in fresh water – only swim in the sea or chlorinated swimming pools. boil or filter water before drinking – as the parasites could burrow into your lips or mouth if you drink contaminated water.
Is there a pertussis vaccine?
There are 2 vaccines that include protection against whooping cough: The DTaP vaccine protects young children from diphtheria, tetanus, and whooping cough. The Tdap vaccine protects preteens, teens, and adults from tetanus, diphtheria, and whooping cough.
Can schistosomiasis be transmitted from person to person?
A person with schistosomiasis cannot pass it on to another person. Humans only become infected through contaminated water where the snails are living.
How does schistosomiasis affect the body?
Without treatment, schistosomiasis can persist for years. Signs and symptoms of chronic schistosomiasis include: abdominal pain, enlarged liver, blood in the stool or blood in the urine, and problems passing urine. Chronic infection can also lead to increased risk of liver fibrosis or bladder cancer.
Who should not take praziquantel?
You should not use praziquantel if you are allergic to it, or if: you have a parasitic infection in your eye; or. you have taken rifampin within the past 4 weeks.