What is cystoid macular edema?

Cystoid macular edema or CME, is a painless disorder which affects the central retina or macula. When this condition is present, multiple cyst-like (cystoid) areas of fluid appear in the macula and cause retinal swelling or edema.

What are the symptoms of cystoid macular edema?

What Are the Symptoms of Cystoid Macular Edema? Patients with cystoid macular edema frequently notice their reading vision is blurred. The peripheral or side vision remains unchanged. Frequently, people with cystoid edema notice distortion of objects and dimness.

What is refractory macular edema?

All eyes that received the intravitreal FAc implant had refractory DME, characterized by cystoid macular edema (CME) defined as the accumulation of fluid in well-defined round hyporeflective spaces within the outer plexiform layer on spectral-domain optical coherence tomography (SD-OCT) associated with loss of the …

Is there a difference between macular edema and cystoid macular edema?

Sometimes the macula becomes swollen with fluid. When any tissue of the body becomes swollen with fluid, the condition is called edema. When this happens to the macula, the edema fluid typically combines in cyst-like patterns; this condition is called cystoid macular edema.

What is persistent DME?

Probability of Chronic Persistent Diabetic Macular Edema (DME) An event is defined as a central subfield thickness less than 250 μm and a 10% or greater reduction relative to the 24-week study visit on at least 2 consecutive study visits subsequent to the 24-week visit.

Is CME curable?

Cystoid macular edema after cataract surgery usually has an excellent prognosis with the majority of cases responding to medical treatment. Once the CME resolves, the vision typically returns back to normal. Some CME that becomes chronic, lasting years, can lead to permanent vision loss.

Are corticosteroids effective in the treatment of pseudophakic macular edema?

The literature reporting their efficacy in macular edema is mainly in diabetic or retinal vein occlusion eyes. Their efficacy in pseudophakic CME is unknown. Side effects of periocular and intravitreal corticosteroids include endophthalmitis and elevated intraocular pressure.

What are the signs and symptoms of pseudophakic cataract surgery?

Reduced visual acuity following cataract surgery is the most common clinical finding in pseudophakic CME. The onset is typically four to 12 weeks after surgery, reaching a peak incidence four to six weeks postoperatively. Patients may complain of metamorphopsia, central scotoma and reduced contrast sensitivity.

How is pseudophakic central macular degeneration (CME) diagnosed?

FA is the gold standard in diagnosing pseudophakic CME, but treatment responses would be more conveniently monitored by biomicroscopy, visual acuity and OCT. Optical coherence tomography ( OCT) (image to the left) allows high-resolution cross-sectional imaging of the macula.

Which angiogram findings are characteristic of pseudophakic cystoid macular edema?

Fluorescein angiogram of a right eye with pseudophakic cystoid macular edema. Early frame discloses leakage of the perifoveal capillaries (upper left) that increases in size and intensity to a “petaloid” appearance in the later frame (upper right).