How much does recombinant cost?

Product (Manufacturer) Source Average Cost Per Dose ($)a,b
Recombinate® (Baxter Hyland/Immuno) Recombinant 4,480
Kogenate FS® (Bayer) Recombinant 4,130
Helixate FS® (Aventis Behring) Recombinant 4,130
Refacto® (Genetics Institute) Recombinant 4,760

What is the cost of factor VIII?

In that year, the price of factor VIII averaged 2.53 U.S. dollars in the United States. Factor VIII is a drug used, for example, to treat patients with hemophilia A….Average prices of factor VIII in selected countries in 2017 (in U.S. dollars)*

Characteristic Average price in U.S. dollars
United States 2.53

How long does advate last?

Advate is usually given every 8 to 24 hours for 1 to 4 days, depending on the reason you are using the medicine. This medicine comes with patient instructions for safe and effective use.

How much does Kogenate cost?

The cost for Kogenate FS intravenous powder for injection recombinant is around $10 for a supply of 1 powder for injection, depending on the pharmacy you visit….Intravenous Powder For Injection.

Quantity Per unit Price
1 $10.16 $10.16

How much is Eloctate cost?

The cost for Eloctate intravenous powder for injection recombinant fc fusion protein is around $12 for a supply of 1 powder for injection, depending on the pharmacy you visit….Intravenous Powder For Injection.

Quantity Per unit Price
1 $11.90 $11.90

Is hemophilia treatment expensive?

The cost of drug therapy for a person with hemophilia can be several hundred thousand dollars per year and annual treatment costs of $1 million or more are not unheard of for patients with the most severe forms of the disease.

Why are hemophilia drugs so expensive?

Not only do prices rise steadily as each new product comes on the market, demand is growing — and pushing costs upward — as more and more clotting factor is used to prevent bleeding episodes, not just to treat them.

How much does advate cost?

The cost for Advate intravenous powder for injection (recombinant albumin-free) is around $11 for a supply of 1 powder for injection, depending on the pharmacy you visit….Intravenous Powder For Injection.

Quantity Per unit Price
1 $11.32 $11.32

Where is advate manufactured?

In December 2000 production of ADVATE commercial scale lots commenced at a dedicated manufacturing facility in Neuchatel, Switzerland.

Who manufactures Kogenate?

Manufacturing – Product safety and quality Bayer places a high priority on product quality throughout the Kogenate FS manufacturing process.

What is recombinate™ (recombinant)?

There are some things in life that work for you, like controlling and preventing bleeds with RECOMBINATE™ [Antihemophilic Factor (Recombinant)]. 1 As the first genetically engineered factor VIII concentrate, RECOMBINATE changed the approach to hemophilia A treatment when it was first available in the United States in 1992. 2

What is the shelf life of recombinate?

Reconstituted product (after mixing dry product with wet diluent) must be used within 3 hours and cannot be stored or refrigerated. Any RECOMBINATE left in the vial at the end of your infusion should be discarded. How is RECOMBINATE supplied?

What is the actual baseline recovery time for recombinate?

The actual baseline recovery observed with RECOMBINATE was 123.9 ± 47.7 IU/dL (n=23), which is significantly higher than the actual HEMOFIL M baseline recovery of 101.7 ± 31.6 IU/dL (n=61).

Can the baxject II device be used with multiple vials?

The BAXJECT II device should be used only with the intended product. The BAXJECT II device is intended for use with a single vial of product and is for single use only. Therefore, reconstitution and withdrawing a second vial into the syringe requires a second BAXJECT II device.