Which statin has the least reported side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.

Which statin was removed from the market?

On Aug 8, German drug company Bayer AG announced the withdrawal of its cholesterol-lowering drug cerivastatin after it was linked to the deaths of 52 patients in the USA and Europe.

What is the least potent statin?

In general, rosuvastatin, atorvastatin and simvastatin are considered to be the most potent statins and fluvastatin, pravastatin and lovastatin less potent.

What’s the difference between rosuvastatin and atorvastatin?

Rosuvastatin provided significantly greater LDL-C reductions than atorvastatin, both at the initial dose of 10 mg and also when titrated over the dose range of 10–40 mg for rosuvastatin and 10–80 mg for atorvastatin.

Which statin has the least myopathy?

These can be especially useful in patients with symptoms or risk of myopathy. Pravastatin has been considered by many as the only safe statin with regard to myopathy. Evidence in the scientific literature, however, is actually stronger for fluvastatin as having the lowest myopathy risk.

Which is better Crestor or atorvastatin?

Crestor (rosuvastatin) is more potent and causes a more significant lowering of total cholesterol, but Crestor and Lipitor (atorvastatin) similarly decrease the buildup of plaques in the blood vessels.

What are the possible side effects of statins?

J Am Coll Cardiol 2016;67:2395-2410. The following are key points to remember about statin-associated side effects: Statins are generally well tolerated, but can be associated with skeletal muscle, metabolic, central nervous system complaints, and possibly other side effects.

What are the side effects of statins for rhabdomyolysis?

Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million of patients taking statins.

How do I know if I should take a break from statins?

Take a brief break from statin therapy. Sometimes it’s hard to tell whether the muscle aches or other problems you’re having are statin side effects or just part of the aging process. Taking a break can help you determine whether your aches and pains are due to statins instead of something else. Switch to another statin drug.

Should statins be stopped for statin-induced SARS?

If low vitamin D levels, hypothyroid, and drug interactions are eliminated, and the statin is stopped until symptoms disappear; statins with a long half-life (atorva, rosuva, pitava) given low dose and less often can result in over 90% of patients with SAS being able to tolerate a statin.