Is a myofibroblastic tumor cancer?
IMT is usually benign, meaning that it is not cancer and these tumor cells usually do not travel to other parts the body. However, IMT can invade nearby tissue and cause a lot of problems. IMT can grow in the way of important organs such as the lung or stomach. In very rare cases, IMT can spread to distant organs.
How do you treat inflammatory myofibroblastic tumors?
When necessary, surgical resection could be considered the preferred treatment for IMT, which can also be used to confirm this disease. The recurrence rate has been reported to range from 18% to 40%, and only precise removal of the tumor will avoid recurrence.
What is IMT lungs?
Inflammatory myofibroblastic tumors (IMT) of the lung, first reported in 1939, are considered a subset of inflammatory pseudo -tumors. They are a distinctive lesions composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils.
What is inflammatory pseudotumor?
Inflammatory pseudotumor (IPT) is a term used to describe a benign and rare process most commonly involving the lung and orbit but found in nearly every site in the body. This entity has been described by several names and histologic presentations and as mimicking neoplastic processes.
What is myofibroblastic?
Myofibroblasts are specialized fibroblasts with contractile activity. They form within wounds in response to tissue plane stress and the secretion of TGF-β by platelets and macrophages as wounds develop, and they increase in number with time and severity.
Does pseudotumor go away?
With treatment, the pressure in your brain will go down. You should start to feel better within a few months. Most people completely recover, but a few will have permanent vision loss. Because pseudotumor cerebri can come back, see your doctor for follow-up visits and get regular eye checkups.
Is inflammatory myofibroblastic tumor sarcoma?
Inflammatory myofibroblastic tumors usually occur in children and young adults. They are a type of soft tissue sarcoma.
Is IMT a sarcoma?
A variant of IMT known as epithelioid inflammatory myofibroblastic sarcoma (EIMS), as described in our case, displays a malignant behavior with a high potential for recurrence and is associated with a poor prognosis (7,8).
What is myofibroblastic proliferation?
Background. Pseudosarcomatous myofibroblastic proliferation (PMP) is a rare disease entity of unknown etiology and pathogenesis. PMP is also known as an inflammatory pseudotumor (IPT) or inflammatory myofibroblastic tumor (IMT), and it is characterized by myofibroblast proliferation and inflammatory cell infiltration.
Does sarcoma grow fast?
The general characteristics of most sarcomas are that they grow quickly, are located deep within tissue, and are relatively large.
Is pseudotumor cerebri an emergency?
Pseudotumor cerebri is a medical emergency since it can cause blindness. Treatment usually is effective, and most people have no or minimal vision loss. Pseudotumor cerebri can return after treatment, but keeping a healthy weight may help to prevent this.
Pseudosarcomatous myofibroblastic proliferation (PMP) is a rare disease entity of unknown etiology and pathogenesis. PMP is also known as an inflammatory pseudotumor (IPT) or inflammatory myofibroblastic tumor (IMT), and it is characterized by myofibroblast proliferation and inflammatory cell infiltration.
What is the treatment for a solitary fibrous tumor?
Solitary fibrous tumor. Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura.