Which drug is used as antihypertensive?

Pharmacological management of hypertension

Class Examples
β-Blockers Atenolol, metoprolol, propranolol
α-Blockers Doxazosin, labetalol (also a β-blocker), phentolamine, phenoxybenzamine
Calcium channel blockers
Phenylalkamines Verapamil

What are systemic medications?

Systemic treatments, aimed at those with varying degrees of psoriasis and psoriatic disease severity, are prescription drugs that work throughout the body. They are also used in those who are not responsive or are unable to tolerate topical treatments or phototherapy.

Which drugs are beta blockers?

Examples of beta blockers

  • Acebutolol.
  • Atenolol (Tenormin)
  • Bisoprolol (Zebeta)
  • Metoprolol (Lopressor, Toprol XL)
  • Nadolol (Corgard)
  • Nebivolol (Bystolic)
  • Propranolol (Inderal, InnoPran XL)

What is the second line treatment for hypertension?

ACE inhibitors and ARBs are preferred agents in the management of patients with hypertension and diabetes. If target blood pressure is not achieved with an ACE inhibitor or ARB, addition of a thiazide diuretic is the preferred second-line therapy for most patients with diabetes.

What are the most common antihypertensive drugs?

Common Medications for High Blood Pressure

  • Amlodipine (Norvasc) is a calcium channel blocker.
  • Benazepril (Lotensin) is an ACE inhibitor.
  • Chlorthalidone (Hygroton) is a thiazide diuretic.
  • Enalapril (Vasotec) is an ACE inhibitor.
  • Hydrochlorothiazide (Hydrodiuril, Microzide) is a thiazide diuretic.

Is heparin an antihypertensive?

Chronic subcutaneous administration of heparin consistently lowers blood pressure in hypertensive rats. This antihypertensive effect is related at least in part to a concomitant decrease in hematocrit.

What are non systemic drugs?

Non-systemic drugs act within the intestinal lumen without reaching the systemic circulation. The first generation included polymeric resins that sequester phosphate ions, potassium ions, or bile acids for the treatment of electrolyte imbalances or hypercholesteremia.

What are beta blockers for anxiety?

Propranolol and atenolol are two beta-blockers that are often prescribed to help with anxiety. Using a drug off-label means that a drug has been approved by the FDA for one purpose, and it’s being used for a different purpose that hasn’t been approved.

What is Omapatrilat used to treat?

Omapatrilat is a dual inhibitor of both ACE and NEP, which has been evaluated for the treatment of hypertension and heart failure.

Is Omapatrilat a dipeptide?

Omapatrilat is a dipeptide. Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling.

Can enalapril and Omapatrilat be used to treat class II heart failure?

Methods and Results— We randomly assigned 5770 patients with New York Heart Association class II to IV heart failure to double-blind treatment with either the ACE inhibitor enalapril (10 mg BID, n=2884) or to the ACE-NEP inhibitor omapatrilat (40 mg once daily, n=2886) for a mean of 14.5 months.