What is delayed neurologic sequelae?

Delayed neurologic sequelae (DNS) are recurrent–transient neuropsychiatric consequences of carbon monoxide (CO) intoxication. They manifest with alternating periods of exacerbation and remission that cause diffuse white matter or gray matter injury.

Can you have a delayed reaction to carbon monoxide?

But unlike flu, carbon monoxide poisoning does not cause a high temperature. The symptoms can gradually get worse with prolonged exposure to carbon monoxide, leading to a delay in diagnosis. Your symptoms may be less severe when you’re away from the source of the carbon monoxide.

How long does it take to get brain damage from carbon monoxide?

An unusual feature of acute CO poisoning is the delayed deterioration in neurological condition which may be seen in some cases, occurring anything from a few days to as long as five to six weeks after the initial exposure.

What is delayed encephalopathy?

Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is a serious and common complication of exposure to CO at toxic levels (9,10). DEACMP manifests as memory impairment, cognitive dysfunction and behavioral disorders that develop several days or weeks after acute exposure to CO (9,10).

How long does neurological sequelae delay last?

DNS are reported to occur in 5% to 26% of patients after CO poisoning and are characterized by the presence of a clinically silent or lucid intervals, lasting about 2 to 6 weeks after exposure,[1,2] and followed by the development of DNS, including a broad spectrum of neurological deficits, cognitive impairments, and …

How does carbon monoxide poisoning affect the brain?

Studies have indicated that CO may cause brain lipid peroxidation and leukocyte-mediated inflammatory changes in the brain, a process that may be inhibited by hyperbaric oxygen therapy. Following severe intoxication, patients display central nervous system (CNS) pathology, including white matter demyelination.

Does carbon monoxide cause permanent brain damage?

Depending on the degree and length of exposure, carbon monoxide poisoning can cause: Permanent brain damage. Damage to your heart, possibly leading to life-threatening cardiac complications. Fetal death or miscarriage.

What are the long term health effects of exposure to carbon dioxide gas?

Exposure to CO2 can produce a variety of health effects. These may include headaches, dizziness, restlessness, a tingling or pins or needles feeling, difficulty breathing, sweating, tiredness, increased heart rate, elevated blood pressure, coma, asphyxia, and convulsions.

Can you lose brain cells from carbon monoxide?

Depending on the degree and length of exposure, carbon monoxide poisoning can cause: Permanent brain damage.