What is bupropion chemical structure?
Amfebutamone(Bupropion) 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydrochloride. 1-(3-CHLOROPHENYL)-2-[(1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE HYDROCHLORIDE. DSSTox_CID_24561.
What is bupropion chemically similar to?
Its efficacy as an antidepressant is comparable to that of tricyclic antidepressants, and as a serotonin uptake inhibitor it is comparable to fluoxetine. It is preferable to use amoxapine. Synonyms of bupropion are amphebutamon and wellbutrin.
How does wellbutrin work chemically?
Wellbutrin, also known as bupropion, is one of the more commonly prescribed antidepressants. The drug is a norepinephrine-dopamine reuptake inhibitor, or NDRI. Basically, the medication alters a person’s mood by increasing dopamine levels in the brain.
What does bupropion hydrochloride do?
Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders.
Is Bupropion a ketone?
Bupropion is classified as a monocyclic phenylbutylamine of the amino ketone group. It selectively blocks dopamine uptake and is 6 times more potent than imipramine and 19 times more potent than amitriptyline in blocking dopamine reuptake.
Is Bupropion a controlled substance?
Bupropion is not a controlled substance.
What is bupropion hydrochloride made of?
It is designated as (±)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1 propanone hydrochloride. The molecular weight is 276.2. The molecular formula is C13H18ClNO•HCl. Bupropion hydrochloride powder is white, crystalline, and highly soluble in water.
Is bupropion a ketone?
Is Bupropion a dopamine agonist?
One of these drugs is bupropion, a norepinephrine-dopamine reuptake inhibitor, which is widely used as an antidepressant or as an aid to smoking cessation. Because of its dopaminergic mechanisms of action, bupropion has also shown some efficacy for dopamine agonist-mediated compulsive behaviors7 and apathy8 in PD.
What chemicals does Wellbutrin affect?
Bupropion, or Wellbutrin, is different. It is a norepinephrine-dopamine reuptake inhibitor (NDRI). An NDRI boosts levels of the neurotransmitters norepinephrine, also known as noradrenaline, and dopamine. Its action is complex, and its neurological effects are only partly understood.
Is bupropion used for anxiety?
In addition to having a favorable side effect profile, bupropion has been shown to have positive results in treating anxiety associated with depression compared with sertraline and fluoxetine.
Is bupropion water soluble?
Bupropion hydrochloride powder is white, crystalline, and highly soluble in water. It has a bitter taste and produces the sensation of local anesthesia on the oral mucosa.
Who should not take Wellbutrin?
You should not take Wellbutrin if you have seizures, an eating disorder, or if you have suddenly stopped using alcohol, seizure medications, or sedatives. If you take Wellbutrin for depression, do not also take Zyban to quit smoking. Do not use Wellbutrin if you have used an MAO inhibitor in the past 14 days.
How quickly does bupropion work?
It depends: That would depend to some extent on the condition being treated, the dosing used, and the delivery method (oral vs im). In general the earliest effect would be in about 3-7 days with further increase in effect over the next 4-6 weeks.
How does bupropion affect brain?
Bupropion is an antidepressant medication that affects chemicals within the brain that nerves use to send messages to each other. These chemical messengers are called neurotransmitters. Many experts believe that depression is caused by an imbalance among the amounts of neurotransmitters that are released.
When is the best time to take Wellbutrin?
Wellbutrin (bupropion) should be taken in the morning according to the prescribing information. In some individuals, Wellbutrin can cause insomnia (trouble falling asleep). To avoid or limit the risk of insomnia, Wellbutrin should not be taken in the evening or at night time.