What is a good vitamin B12 test result?
Understanding the Results But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.
What is the binding protein for vitamin B12?
The vitamin B12 (cobalamin) binding proteins, transcobalamin and haptocorrin, were measured in serum and synovial fluid of 12 patients with rheumatoid arthritis (RA) and 11 patients with traumatic synovitis (TS).
What is normal range B12?
Normal values are 160 to 950 picograms per milliliter (pg/mL), or 118 to 701 picomoles per liter (pmol/L). Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about what your specific test results mean.
What is vitamin B12 binding capacity?
Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin) – Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin), binds and transports vitamin B12 in the circulation. Increased concentrations are associated with patients with myeloproliferative disorders.
What is R binder?
Types. Transcobalamin I (TCN1), also known as haptocorrin, R-factor, and R-protein, is a glycoprotein produced by the salivary glands of the mouth. It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex.
Is transcobalamin II affinity for vitamin B12 related to neural tube defects?
Background: Transcobalamin II is a serum transport protein for vitamin B12. Small variations in TC-II affinity were recently linked to a high homocysteine level and increased frequency of neural tube defects.
What does transcobalamin mean?
Vitamin B 12 Binding Capacity, Unsaturated (Transcobalamin) – Vitamin B 12 Binding Capacity, Unsaturated (Transcobalamin), binds and transports vitamin B 12 in the circulation. Increased concentrations are associated with patients with myeloproliferative disorders.
Is transcobalamin II deficiency hereditary?
Hereditary Partial Transcobalamin II Deficiency With Neurologic, Mental and Hematologic Abnormalities in Children and Adults We report the first family with a hereditary transmitted condition of low serum TC-II (partial TC-II deficiency) associated with neurologic and mental manifestations in childhood.
What causes vitamin B12 deficiency in megaloblastic anemia?
Complete absence of TC-II or total functional abnormality causes tissue vitamin B12 deficiency resulting in a severe disease with megaloblastic anemia and immunologic and intestinal abnormalities in the first months of life. This condition was described in hereditary autosomal-recessive form.