What is Saroglitazar used for?
Saroglitazar is a dual peroxisome proliferator-activated receptor (PPAR) inhibitor that is used to treat high cholesterol in people with diabetes (diabetic dyslipidemia). It aids in the management of high cholesterol, especially triglycerides, as well as blood sugar levels in people with type 2 diabetes.
Is Saroglitazar safe?
Saroglitazar treatment was generally safe and well tolerated. No serious adverse events were reported in saroglitazar treatment arm and no persistent change in laboratory parameters.
Is Saroglitazar FDA approved?
Zydus, a leading discovery based, global pharmaceutical company announced that United States Food and Drug Administration (FDA) has granted “Fast Track Designation” to Saroglitazar Mg for the treatment of patients with primary biliary cholangitis (PBC).
Is Saroglitazar a statin?
It is approved for use in India by the Drug Controller General of India. Saroglitazar is indicated for the treatment of diabetic dyslipidemia and hypertriglyceridemia with type 2 diabetes mellitus not controlled by statin therapy….Saroglitazar.
|3D model (JSmol)||Interactive image|
Is Saroglitazar good for liver?
Saroglitazar, a dual peroxisome proliferator activated receptor α/γ agonist, approved for diabetic dyslipidemia (DD), is potential therapeutic option for non-alcoholic fatty liver disease (NAFLD).
When should Saroglitazar tablets be taken?
It is best to take Saroglitazar before the first meal of the day. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Saroglitazar.
Can Saroglitazar cause hypoglycemia?
After addition of saroglitazar, patient started complaining of hypoglycemic episodes which lead to decrease in insulin daily dose. After 9 months treatment with saroglitazar, the dose of insulin was reduced to 44 units per day. The patient is stable with controlled glycemic parameters.
What is Obeticholic acid used for?
Obeticholic acid is used alone or in combination with ursodiol (Actigall, Urso) to treat primary biliary cholangitis (PBC; a type of liver disease that destroys bile ducts, which allows bile to stay in the liver and cause damage) in people who cannot take ursodiol or in people who were not treated successfully with …
Does Saroglitazar cause weight loss?
Saroglitazar exerted its beneficial effects on adipose tissue by limiting, diet-induced adipose tissue dysfunction, adipocyte hypertrophy, adipocyte cell damage and extracellular matrix deposition in obesity. Keywords: Energy expenditure; Extracellular remodeling; Inflammation; Insulin resistance; Obesity; PPARs.
Does Lipaglyn cause weight loss?
Is there a chance of weight gain with Lipaglyn Tablet? It has been observed from clinical research conducted on Lipaglyn Tablet that there is no significant risk of weight gain in patients taking Lipaglyn Tablet.
When should I take Obetohep 5?
Obetohep 5mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it.
What is another name for Obeticholic acid?
|Other names||6α-ethyl-chenodeoxycholic acid; INT-747|
Is Saroglitazar available in India?
Saroglitazar (INN, trade name Lipaglyn) is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia. It is approved for use in India by the Drug Controller General of India.
What are the side effects of saroglitazar?
There are no reported side effects of Saroglitazar. Saroglitazar is only available in form of tablets to be taken orally. It comes in packets of 10 tablets each of 4mg and should be taken only if recommended by a doctor, as per the prescribed dosage.
What is the best time of day to take Saroglitazar?
The primary endpoint of the study is percentage change from baseline in serum ALT levels at Week 16 in the Saroglitazar Magnesium groups as compared to the placebo group. Saroglitazar magnesium 1 mg tablet orally once daily in the morning before breakfast for 16 weeks.
What is the structure of saroglitazar?
Saroglitazar is a monocarboxylic acid that is (2S)-2-ethoxy-3- (p-ethoxyphenyl)propanoic acid in which one of the methyl hydrogens of the p-ethoxy substituent has been replaced by the nitrogen of 2-methyl-5- [4- (methylthio)phenyl]-1H-pyrrole.